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Confinia Cephalalgica, a peer-reviewed open access journal, focuses on publishing articles related to various aspects of headache medicine, including genetics, pathophysiology, diagnosis, imaging, management, epidemiology, pharmacology, and treatment. It covers both primary and secondary headaches, as well as other facial pains and their connections with systemic diseases. Confinia Cephalalgica highlights the historical context of scientific advancements in headache medicine, particularly the recent innovative investigations and their impact on migraine treatment. The journal aims to stay updated with rapidly evolving areas of medicine, such as digital health, gender medicine, and artificial intelligence, as applied to the field of headache medicine. The journal publishes quarterly issues containing various types of articles, including original and review articles, case reports, short communications, letters to the editor, and news items as "pros and cons" articles discussing controversial basic and clinical issues.

Confinia Cephalalgica is the official journal of the Italian Society for the Study of Headaches (SISC) with the overarching goal to serve as a forum for scientists and clinicians dedicated to headache medicine.

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  • Anti-CGRP monoclonal antibodies improve cognitive function in patients affected by chronic migraine complicated with medication overuse-headache

    Simona Guerzoni, Flavia Lo Castro, Carlo Baraldi, Daria Brovia, Fabio Tascedda, Veronica Rivi, Luca Pani
    https://doi.org/10.4081/cc.2024.15760
    948
    PDF: 297

  • Cortical excitability in patients with migraine with aura and depressive symptoms: a visual evoked potentials study

    Francesco Casillo, Chiara Abagnale, Gabriele Sebastianelli, Antonio Di Renzo, Vincenzo Parisi, Ettore Cioffi, Mariano Serrao, Cherubino Di Lorenzo
    https://doi.org/10.4081/cc.2024.15764
    900
    PDF: 307

  • ID-Migraine test for pediatric population: preliminary results from the Italian validation

    Ilaria Frattale, Laura Papetti, Fabiana Ursitti, Giorgia Sforza, Gabriele Monte, Luigi Mazzone, Massimiliano Valeriani
    https://doi.org/10.4081/cc.2024.15761
    1051
    PDF: 274

  • Normative values of the nociceptive blink reflex habituation

    Michele Corrado, Elena Mazzotta, Gloria Vaghi, Francescantonio Cammarota, Federico Bighiani, Alessandro Antoniazzi, Daniele Martinelli, Maria Magdalena Pocora, Luca Martinis, Valentina Grillo, Sara Bottiroli, Armando Perrotta, Giuseppe Cosentino, Grazia Sances, Cristina Tassorelli, Roberto De Icco
    https://doi.org/10.4081/cc.2024.15730
    724
    PDF: 212
    SUPPLEMENTARY MATERIAL: 162

  • Prospective evaluation of aura during anti-calcitonin gene-related peptide monoclonal antibody therapy after 52 weeks of treatment

    Marina Romozzi, Andrea Burgalassi, Catello Vollono, Maria Albanese, Giulia Vigani, Francesco De Cesaris, Alberto Chiarugi, Paolo Calabresi, Luigi Francesco Iannone
    https://doi.org/10.4081/cc.2024.15762
    1201
    PDF: 201